The Ultimate Guide To indazole nmr
Substitution at R3 having a halogen or alkoxy group (74f–74i) led to a slight rise in mobile potency While using the halide analogs (74g–h) showing best the potency inside the group. More optimization resulted in the invention of 74i–j, with 74k as the most Lively compound while in the collection (pIC50 = six.seventy seven) with fantastic LLE